This is a summary of a video uploaded on CNA Insider Nov, 2022. Dr Daryl teamed up with NUS Yong Loo Lin School of Medicine using Artificial Intelligence to create bespoke treatments for Donavan, a 24-year-old cancer patient with Stage 4 natural killer (NK) cell lymphoma.

Lymphoma Treatment with personalised medicine in SingaporeImage credit:

What is Natural Killer (NK) cell Lymphoma?

Lymphoma is a cancer that starts in infection-fighting white blood cells called lymphocytes, which are part of the body’s immune system, according to the National University Cancer Institute, Singapore (NCIS). Natural killer (NK) cell lymphoma, a “very rare” variant of lymphoma.

Finding the best drug combinations

From a set of 12 drugs chosen by the researchers, Quadratic Phenotypic Optimisation Platform (QPOP) generates over half a million drug combinations that were possible for Donavan, then ranked the different drug cocktails and identified the most effective one for him

Patient’s response to the treatment

After the first few rounds of lymphoma treatment, the bespoke drug combination helped Donavan fend off the disease for 16 months.

About Dr Daryl Tan

Dr Daryl Tan is an experienced haematologist who specialises in the treatment of blood cancers, including lymphoma, multiple myeloma, leukaemia, and myeloproliferative neoplasms. He also has expertise in diagnosing and treating bleeding disorders and general haematological conditions.

Seeking medical advice for your blood cancer or haematological condition? Contact Dr Daryl Tan today.

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